F11IL1702

Anti-Human IL-17A, PE (Clone:64DEC17) 流式抗体 (新品)

¥1,192.00 – ¥2,640.00

说明书

分子靶点：IL17A, IL17, CTLA8
种属：人 (Human)
标记：PE
亚型：Mouse IgG1, κ
克隆号：64DEC17

在售SKU, 70-AH0I1704-20, 70-AH0I1704-50, 70-AH0I1704-100, AH0I1704, 70-F11IL1702-25, 70-F11IL1702-100

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Size
库存号

描述

文章目录[隐藏]

结果示例
分子信息
IL17A 分子靶点信息概述
IL17A 分子靶点综述
- 人 Human IL17A 分子靶点信息
- 人 Human IL17A靶点分子功能（预测）

商品名	Anti-Human IL-17A, PE (Clone:64DEC17) 流式抗体
靶点	IL17A, IL17, CTLA8
标记	PE
仪器	适用488nm, 532nm, 561nm激光器的流式细胞仪
亚型	Mouse IgG1, κ
克隆号	64DEC17
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 图. 人肝素抗凝血经 PMA/Ionomycin (Cat No. CS1001) 刺激和 BFA/Monensin (Cat No. CS1002) 阻断后，染色 Anti-Human CD8α, PerCP-Cy5.5 (F1100804) 和 Mouse IgG1 Isotype Control, PE(CMG104) (左)和 Anti-Human CD8α, PerCP-Cy5.5 (F1100804) 和 Anti-Human IL-17A, PE ( 右) 的结果。以 CD3+细胞设门分析。已排除黏连细胞。

分子信息

概述人 IL17A, IL17, CTLA8 靶点信息

IL17A 分子靶点信息概述

分子名：IL17A, interleukin 17A
基因家族：Interleukins
别名：IL-17A; IL-17
曾用名：CTLA8; IL17
全称：cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

IL17A 分子靶点综述

IL-17主要由Th17型细胞产生，是目前已发现的30余种白细胞介素中的一员，按序号排在第17位。该家族包括6个成员配体(IL-17A ~ IL-17F)和5个受体(IL-17RA ~ IL-17RD和SEF)。IL-17是一种主要由活化的T细胞产生的致炎细胞因子，可以促进T细胞的激活和刺激上皮细胞、内皮细胞、成纤维细胞产生多种细胞因子，从而导致炎症的产生。

人 Human IL17A 分子靶点信息

分子名：IL17A, interleukin 17A
别称：
- CTLA-8
- CTLA8
- cytotoxic T-lymphocyte-associated antigen 8
- cytotoxic T-lymphocyte-associated protein 8
- cytotoxic T-lymphocyte-associated serine esterase 8
- IL-17
- IL-17A
- IL17
- ILA17
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
- interleukin-17
- interleukin-17A
基因序列：NCBI_Gene: 3605
蛋白序列：UniProtKB: Q16552

人 Human IL17A靶点分子功能（预测）

Predicted to enable cytokine activity; protein heterodimerization activity; and protein homodimerization activity. Involved in several processes, including interleukin-17-mediated signaling pathway; positive regulation of cytokine production; and positive regulation of osteoclast differentiation. Acts upstream of or within positive regulation of cytokine production and positive regulation of transcription by RNA polymerase II. Predicted to be located in extracellular region. Implicated in Mycobacterium avium complex disease; autoimmune disease (multiple); bronchial disease (multiple); macular degeneration; and rhinitis (multiple). Biomarker of several diseases, including acne; autoimmune disease (multiple); eye disease (multiple); lung disease (multiple); and rhinitis (multiple).

操作步骤

文章目录[隐藏]

结果示例
分子信息
IL17A 分子靶点信息概述
IL17A 分子靶点综述
- 人 Human IL17A 分子靶点信息
- 人 Human IL17A靶点分子功能（预测）
使用方法
注意事项
FCM流式检测常见问题
查看更多FCM流式检测相关问题

下载本产品说明书

使用方法

将样本经适当处理后，取 100 ?l 含有 1×10⁵ - 10⁸ 个单细胞悬液，加入 5 ?l Anti-Human IL-17A, PE 或同质量的 Mouse IgG1 Isotype Control, PE (Cat No. CMG104)。震荡混匀，室温避光孵育 15 分钟。如进行 Th17 检测，可参考 Human Th17 Staining Kit (Cat No. KTH117)中的实验方案。
实验中，可对抗体进行优化滴定以获得最佳效果。