Mouse CXCL10/IP-10 Standard (小鼠C-X-C基序趋化因子10 标准品)

CXCL10 分子靶点信息概述

• 分子名：CXCL10, C-X-C motif chemokine ligand 10
• 基因家族：Chemokine ligands
• 别名：IFI10; IP-10; crg-2; mob-1; C7; gIP-10
• 曾用名：INP10; SCYB10
• 全称：small inducible cytokine subfamily B (Cys-X-Cys), member 10; chemokine (C-X-C motif) ligand 10

CXCL10 分子靶点综述

趋化因子配体10(CXCL10)又称为γ-干扰素诱导蛋白10(IP-10)或微小诱导细胞因子B10，是属于CXC趋化因子家族的小分子量细胞因子。多种类型的细胞对IFN-γ产生应答后可分泌IP-10，包括单核细胞、内皮细胞和成纤维细胞等。IP-10具有多种功能，如对单核/巨噬细胞、T细胞、NK细胞和树突细胞的趋化作用，促进T细胞黏附于内皮细胞，抗肿瘤活性和抑制骨髓集落形成和血管生成。

小鼠 Mouse Cxcl10 分子靶点信息

• 分子名：Cxcl10, chemokine (C-X-C motif) ligand 10
• 别称：
  • C7
  • CRG-2
  • gIP-10
  • Ifi10
  • INP10
  • interferon activated gene 10
  • IP-10
  • IP10
  • mob-1
  • Scyb10
  • small inducible cytokine B subfamily (Cys-X-Cys), member 10
• 基因序列：NCBI_Gene: 15945
• 蛋白序列：
  • UniprotKB: P17515
  • UniprotKB: D3YW23
  • UniprotKB: Q3U6X5
  • UniprotKB: Q3UAS6
  • UniprotKB: Q3UCV1
  • UniprotKB: Q3UK71
  • UniprotKB: Q548V9

小鼠 Mouse Cxcl10 靶点分子功能（预测）

Predicted to enable chemoattractant activity; chemokine receptor binding activity; and heparin binding activity. Acts upstream of or within several processes, including defense response to virus; negative regulation of myoblast differentiation; and negative regulation of myoblast fusion. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including alimentary system; axial skeleton; hemolymphoid system; and liver. Human ortholog(s) of this gene implicated in hepatitis B; middle cerebral artery infarction; and type 1 diabetes mellitus. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10).